Cagrilintide 5mg, Semaglutide 5mg Blend

Buy Cagrilintide/Semaglutide Blend: Advanced Dual-Peptide Formulation for Metabolic Research

Innovative Combination for In-Vitro and Preclinical Studies

Peptide Compositions and Structures:

1. Cagrilintide (AM833):
   • Sequence: Modified from native amylin
   • Molecular Weight: Approximately 4,500 Da
   • Structure: Long-acting amylin analog with enhanced stability
2. Semaglutide:
   • Sequence: H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH
   • Molecular Weight: 4,113.58 g/mol
   • Structure: Modified GLP-1 analog with a C18 fatty di-acid chain

Mechanism of Action in Research Models:

1. Cagrilintide:
   • Targets amylin receptors
   • Potential effects on food intake and energy expenditure in animal models
   • May influence nutrient utilization and glucose metabolism in cellular studies
2. Semaglutide:
   • Activates GLP-1 receptors
   • Shown to affect insulin secretion in pancreatic β-cell cultures
   • Potential impact on appetite centers in brain tissue samples

Research Applications:

• In-vitro studies on adipocyte metabolism
• Ex-vivo investigations using pancreatic islet cells
• Animal model research on energy balance and weight regulation
• Cellular signaling pathway analyses in metabolic tissues

Advanced Research Potential:

1. Comparative studies of amylin and GLP-1 receptor activation
2. Investigation of potential synergistic effects on cellular energy metabolism
3. Analysis of combined impact on hypothalamic appetite regulation in brain tissue samples
4. Exploration of dual-peptide influence on glucose uptake in muscle and adipose tissue cultures

Stability and Handling:

• Lyophilized powder for extended shelf life
• Recommended storage at -20°C for optimal stability for long term storage of up to 5 years, room temperature for 1-3 months, or 3-12 months in standard refrigerator temperatures.