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Melanotan II 17mg

$45.00

In stock

Qty Price
1 $45.00
2 - 4 $40.50
5 - 9 $38.25
10 - 14 $34.65
15 - 19 $33.30
20 + $31.50

Only the lyophilized product is provided. All researchers are assumed to have all necessary supplies to conduct their research, such as reconstitution solution and disinfecting aids to maintain Sterility.

[cuw_fbt]
Description
Melanotan II is a synthetic peptide hormone that has been studied for its potential to stimulate melanogenesis and increase sexual arousal. It is an analogue of the peptide hormone alpha-melanocyte-stimulating hormone (α-MSH) and has been found to have several effects on the body.

Structure and Modifications

Melanotan II is a cyclic heptapeptide with the amino acid sequence Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2. This peptide is synthesized using solid-phase synthesis methods, which involve selectively protecting part of the amino acids and adopting different cyclization sequences to obtain the cyclopeptide resin.

Synthesis and Research

Melanotan II is synthesized using a combination of solid-phase and solution-phase methods. The synthesis involves the assembly of the hexapeptide sequence using a [(2+2)+1+1] scheme, followed by a carbodiimide-mediated lactamization to form the cyclic intermediate. The final peptide is then obtained by appending N-acetylnorleucine. Research on Melanotan II has focused on its pharmacokinetic and pharmacodynamic effects. Studies have shown that it binds to melanocortin receptors, particularly MC1R and MC4R, which are expressed primarily in the central nervous system. This binding leads to the stimulation of melanogenesis and increased sexual arousal.

Mechanism of Action

Melanotan II acts as a non-selective agonist of melanocortin receptors, which are involved in various physiological processes such as pigmentation, energy homeostasis, sexual functioning, the immune system, inflammation, and the cardiovascular system.  
CID 92432
Molecular Formula C50H69N15O9
Molecular Weight 1024.2 g/mol
Structure Image Chemical Structure

Latest Lab Results

Janoshik

Janoshik

June 6, 2024

Lab Results:

Avg. Mass: 17.84mg

Avg. Purity: 99.702%

Batch:

POL-M210-1

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