N-Acetyl Selank Amidate 15mg

N-Acetyl Selank Amidate (commonly referred to as NA Selank) is a modified version of the peptide Selank. It has garnered significant attention in recent years due to its potential anxiolytic, nootropic, and anti-inflammatory properties. NA Selank Amidate has been studied extensively in laboratory settings for its effects on anxiety, cognitive function, and neuroprotection.

Structure and Modifications

NA Selank Amidate is a modified version of Selank that has had an acetyl group added to the N-Terminus end of the peptide chain, and an amide group added to the C-Terminus side. These modifications work together to enhance the peptide’s overall stability as well as bioavailability, increasing its potential in biological studies and theoretically enhancing its potential in crossing the blood-brain barrier as well as increasing its interactions with neurotransmitters. The amino acid sequence of NA Selank Amidate is Ac-Thr-Lys-Pro-Arg-Pro-Gly-Pro-NH2.

Pharmacokinetics and Pharmacodynamics

NA Selank Amidate, thanks to its modifications, has a longer half-life compared to the base form of Selank, meaning it remains active for a longer period. This is largely due to its enhanced stability, which resists degradation by enzymes and other factors. This peptide has been studied to modulate the expression of certain genes involved in neurotransmission, especially those in the hippocampus and limbic reticular complex areas, which are parts of the brain critical for both learning and memory.