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PT-141 (Bremelanotide) 15mg

$50.00

Weight/Mass: 15mg

In stock

Qty Price
1 $50.00
2 - 4 $45.00
5 - 9 $42.50
10 - 14 $38.50
15 - 19 $37.00
20 + $35.00

Only the lyophilized product is provided. All researchers are assumed to have all necessary supplies to conduct their research, such as reconstitution solution and disinfecting aids to maintain Sterility.

[cuw_fbt]
Description
PT-141, also known as Bremelanotide, is a synthetic peptide hormone that has gained significant attention in recent years due to its potential to treat sexual dysfunction in both men and women. This peptide is synthesized using solid-phase synthesis methods, which involve selectively protecting part of the amino acids and adopting different cyclization sequences to obtain the cyclopeptide resin.

Structure and Modifications

PT-141 is a cyclic heptapeptide with the amino acid sequence Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH. This peptide is a synthetic version of the naturally occurring alpha-melanocyte-stimulating hormone (α-MSH), which regulates various physiological processes in the body, such as appetite, immune function, and sexual behavior.

Synthesis and Research

PT-141 is synthesized using solid-phase synthesis methods, which involve selectively protecting part of the amino acids and adopting different cyclization sequences to obtain the cyclopeptide resin. Research on PT-141 has focused on its pharmacokinetic and pharmacodynamic effects. Studies have shown that it binds to melanocortin receptors, particularly MC1R and MC4R, which are expressed primarily in the central nervous system.

Pharmacokinetics and Pharmacodynamics

PT-141 works by stimulating melanocortin receptors in the brain, which leads to the release of nitric oxide. The peptide has been found to stimulate the release of nitric oxide, leading to increased blood flow and relaxation of smooth muscles.  
CID 9941379
MolecularFormula C50H68N14O10
MolecularWeight 1025.2
StructureImage Chemical Structure

Latest Lab Results

Janoshik

Janoshik

June 6, 2024

Lab Results:

Avg. Mass: 14.875mg

Avg. Purity: 99.898%

Batch:

POL-PT14110-1

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