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Trifluoroacetic Acid (TFA) (500g)

$825.00

NOTE: May require 2 week lead time. CAS: 76-05-1

Title	Qty	Price
Bulk Discount All Prods	1	0% $825.00
Bulk Discount All Prods	2 - 4	10% $742.50
Bulk Discount All Prods	5 - 9	15% $701.25
Bulk Discount All Prods	10 - 14	23% $635.25
Bulk Discount All Prods	15 - 19	26% $610.50
Bulk Discount All Prods	20 +	30% $577.50

Only the lyophilized product is provided. All researchers are assumed to have all necessary supplies to conduct their research, such as reconstitution solution and disinfecting aids to maintain Sterility.

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Description

Trifluoroacetic acid (TFA) is a versatile and widely used organic solvent with various applications in peptide synthesis and analysis. It is a naturally occurring, biodegradable, and strong acid with a pKa of 0.23, making it an ideal catalyst for various organic transformations.

General Description

TFA is a colorless, volatile, and fuming liquid with a pungent odor. It is miscible with water and various organic solvents, including fluorinated hydrocarbons, methanol, ethanol, ethyl ether, acetone, benzene, carbon tetrachloride, and hexane. Its specific gravity is 1.5351 g/cm³ at 1°C, and it has a melting point of -15.2°C and a boiling point of 72.4°C.

Applications in Peptide Synthesis and Analysis

Peptide Synthesis: TFA is commonly used as a solvent in solid-phase peptide synthesis to cleave peptides from the resin support. It is also used as an ion-pairing agent in reversed-phase high-performance liquid chromatography (RP-HPLC) to improve the separation and detection of peptides.
Mass Spectrometry: TFA is used as a solvent in mass spectrometry for protein identification. It helps to improve the ionization efficiency and stability of peptides during the analysis.
Catalyst: TFA can be used as a catalyst for various organic transformations, including solvolysis, rearrangements, reductions, oxidations, and trifluoromethylation.
Peptide Purification: TFA is used to purify peptides by removing impurities and improving the overall quality of the peptide.
Ion Chromatography: TFA is used as a mobile phase additive in ion chromatography to separate and detect trifluoroacetate ions in peptide samples.

Safety and Handling

TFA is a corrosive and toxic substance that requires proper handling and safety precautions. It can cause skin and eye irritation, and inhalation of its vapors can be harmful. It is also known to be toxic to aquatic organisms and can contribute to greenhouse gas emissions. TFA must be disposed of properly according to local regulations, typically through incineration at an approved facility.

Chemical Info

No chemical information available.

Lab Results

Trifluoroacetic Acid (TFA) (500g)

NOTE: May require 2 week lead time. CAS: 76-05-1

General Description

Applications in Peptide Synthesis and Analysis

Safety and Handling

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Trifluoroacetic Acid (TFA) (500g)

NOTE: May require 2 week lead time. CAS: 76-05-1

General Description

Applications in Peptide Synthesis and Analysis

Safety and Handling

Related Products

Vacufuge plus – Centrifuge Concentrator

Polypropylene Centrifuge Tubes (50 mL) 25-pack

Ammonium Acetate (2.5kg)

HATU (25g)

HBTU (25g)

PyBOP (250g)

Need to get in touch?

Subscribe for exclusive offer updates!

Main Menu

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